In our study, the treatment of non-aggressive BCC with CM derived from MpEV-ATMSC induced the expression of IL6, IL8, and IL1α in these BCC (Figures 3E, F), suggesting the involvement of the PGE2 signaling pathway in the ability of MpEV-ATMSC to induce cancer stemness. Here, CXCL8 is linked to skin basal cell carcinoma.