ALB and Alzheimer disease: NC and AD-MCI groups were selected, and ROC curve indicated that albumin level had the maximum AUC for distinguish NC from AD-MCI (AUC 0.75, 95% CI 0.67–0.82, p < 0.001), with a cut-off value of 41.90 g/L, and sensitivity, specificity, PPV and NPV of 72.86%, 78.08%, 76.12%, and 75.00%, respectively.