SCGB1D2 and skin infection: Recently, a missense variant at the gene encoding for the Secretoglobin family 1D member 2 (SCGB1D2) protein was linked to LB in a large Finnish database (FinnGen), where genetic data was linked to LB diagnosis as recorded by International Classification of Diseases codes [9], This protein is primarily expressed in the skin and sweat glands, and was found to inhibit growth of B. burgdorferi s.l. in vitro, suggesting that SCGB1D2 may have a protective effect on B. burgdorferi s.l. skin infection.