The molecular mechanisms associated to the antitumoral effects of postbiotics include the interaction of short‐chain fatty acids with G protein‐coupled receptors, which has been reported to underlie the inhibition of MMP‐9, which prevents tissue invasion, downregulation of neuropilin‐1, leading to the impairment of angiogenesis and metastasis of CRC cells or enhancement of Bcl‐2‐associated X protein (Bax) expression, which eventually induces apoptosis [9, 56, 57]. Here, MMP9 is linked to colorectal carcinoma.