ORAI1 and colorectal adenocarcinoma: Our results indicate that treatment of the colorectal adenocarcinoma cell lines HT‐29 and Caco‐2 with inanimate Lacticaseibacillus paracasei and Lactiplantibacillus plantarum results in a significant attenuation of SOCE due to downregulation of Orai1 and STIM1 expression.