FH results from variants in the low-density lipoprotein receptor (LDLR, OMIM 606945), apolipoprotein B (APOB, OMIM 107730), and proprotein convertase subtilisin/kexin type 9 (PCSK9, OMIM 607786) genes3. The gene discussed is PCSK9; the disease is familial hyperaldosteronism.