Supporting this notion, we also observed lower frequency of CD4+ T cells, CD8+ T cells andTFH cells, alongside with an overall reduced density of CD21+CD23+ follicular DCs in the mTLSs of HGSOC samples as compared to NSCLC samples (Fig. 4C; Supplementary Fig. 7C). The gene discussed is CR2; the disease is non-small cell lung carcinoma.