TGFB1 and autoimmune disease: Furthermore, TGF-β is widely involved in the fibrosis of many other tissues and diseases as in the cases of cutaneous fibrosis,576,577 muscular fibrosis,578 pancreatic fibrosis,579–582 myelofibrosis,583,584 adenomyosis,585 autoimmune diseases,238,527,573,586–589 and infectious diseases.590–593