Furthermore, while we previously reported no anxiety-like behavioral differences in mice lacking Slc1a1 (Zike et al., 2017), two previous studies reported increased anxiety-like behavior in Slc1a1-KO mice, with one of these studies reporting an increased number of grooming bouts in Slc1a1-KO mice as well (Afshari et al., 2017; Bellini et al., 2018). This evidence concerns the gene SLC1A1 and Anxiety.