In most cases, MX2 mutants that inhibited HIV-1WT infection also enhanced HIV-1G89V CA infection in both HeLa and HT1080 cells (MX1MX2-NTD, SSS14,17,18AAA, YRGK487-490AAAA) while those that did not inhibit the WT virus had no effect on the G89V CA mutant virus (ΔN25, RRR11-13AAA, M574D, R455D) (Figs 3, S6, and S7). The gene discussed is MX2; the disease is infection.