ICAM1 and colitis: For instance, the up-regulation of E-selectin (endothelial-selectin; CD62E); P-selectin (Platelet-selectin; CD62P); intercellular adhesion molecule 1 (ICAM-1); and vascular cell adhesion protein 1 (VCAM-1)] has been reported during TNBS-induced colitis in rats, peaking two weeks after induction of disease [73, 78, 79].