Interestingly, immune-related pathways showed remarkable enrichment, including natural killer cell-mediated cytotoxicity, autoimmune thyroid disease, systemic lupus erythematosus, B cell receptor pathway, Fc gamma R-mediated phagocytosis, complement and coagulation cascades, and intestinal immune network for IgA generation (S1B and S1C Fig) (S1 Table). The gene discussed is CD79A; the disease is systemic lupus erythematosus.