lncRNA NOP14-AS1, ERICH6-AS1, LINC00963, LINC02128 and STAG3L5P-PVPIG2P-PILRB were dramatically upregulated, while GARS1-DT, GMDS-DT, MIR205HG, MIR210HG, and STX18-AS1 were down-regulated in PCOS group. The gene discussed is PILRB; the disease is polycystic ovary syndrome.