Presumably, (R)-DI-87-treatment protects macrophages against AdsA-derived death-effector deoxyribonucleosides and therefore enhances phagocyte survival during abscess formation as (R)-DI-87 neither improved the killing of S. aureus in human or mouse blood, nor it displayed antimicrobial activity (Figure 4—figure supplement 2A–B and Supplementary file 1). This evidence concerns the gene RNF170 and abscess.