SOD1 and myeloid sarcoma: As CPZ is a copper chelator and inhibits copper-dependent enzymes such as superoxide dismutase (SOD), it leads to mitochondrial dysfunction, oxidative stress, selective OLs apoptosis, myelin sheath degeneration, axonal beading, microgliosis, astrogliosis, and neuroinflammation similar to that found in MS (Sen et al. 2022).