AIM2 and breast carcinoma: While the specific ISGs responsible for mediating DC activation still need further identification, the expression analysis of various ISGs, including STAT1, MX dynamin-like GTPase 1 (MX1), C-X-C motif chemokine ligand (CXCL) 10, CXCL9, C–C motif chemokine ligand (CCL) 4, CCL5, HLA class I genes, absent in melanoma 2 (AIM2), and guanylate binding protein 1 (GBP1), in breast carcinoma has demonstrated predictive value for a favorable long-term outcome [121].