However, FTLD-associated pathologies such as TDP-43 proteinopathies (types A and C), as well as three-repeat and four-repeat tauopathies, showed patterns more similar to those found in DLB and AD-related conditions (EOAD, LOAD, PS1) rather than clinical FTD subtypes from a different dataset. The gene discussed is PSEN1; the disease is Alzheimer disease.