We calculated the risk score of individual HCC patients in all cohorts using the following formula: Risk score = [BMI1 expression × (0.1971976)] + [CCR3 expression × (0.2586062)] + [CDC25C expression × (0.181479)] + [CFL1 expression × (0.2796217)] + [LDHA expression × (0.3388622)] + [RAC1 expression × (0.1223471)]. This evidence concerns the gene CFL1 and hepatocellular carcinoma.