GCH1 and hepatocellular carcinoma: Therefore, blocking the pathway and inhibiting the expression of CPX4 can play a synergistic role in inducing ferroptosis, which could provide us with a new method for the future treatment of HCC: CPX4 inhibitors can be combined with GCH1/BH4 pathway inhibitors, and both play a role in inducing ferroptosis in HCC cells to fight tumor proliferation.