Other pathways such as adherens junction, cell cycle, viral carcinogenesis, Hippo signalling pathway, proteoglycans in cancer, colorectal cancer, endometrial cancer, thyroid cancer, chronic myeloid leukemia, hepatitis B, p53 signaling pathway, pathways in cancer, central carbon metabolism in cancer, arrhythmogenic right ventricular cardiomyopathy, PI3-Akt signaling pathway, and melanoma also showed significant moderate associations, as indicated by p-values <0.05 (Fig. 4). The gene discussed is PI3; the disease is hepatitis B virus infection.