Other pathways such as adherens junction, cell cycle, viral carcinogenesis, Hippo signalling pathway, proteoglycans in cancer, colorectal cancer, endometrial cancer, thyroid cancer, chronic myeloid leukemia, hepatitis B, p53 signaling pathway, pathways in cancer, central carbon metabolism in cancer, arrhythmogenic right ventricular cardiomyopathy, PI3-Akt signaling pathway, and melanoma also showed significant moderate associations, as indicated by p-values <0.05 (Fig. 4). This evidence concerns the gene PI3 and thyroid gland carcinoma.