EGR1, identified as a transcription factor activated by vascular injury, has been implicated in the pathogenesis of various vascular diseases, including AAA, TAA, atherosclerosis, myocardial ischemia/reperfusion injury, hypertension, and pathological angiogenesis [[56], [57], [58], [59], [60], [61], [62]]. The gene discussed is EGR1; the disease is hypertensive disorder.