Blood glucose responses (Figure 3A) to SSTR2 antagonist administration (ZT-01) were not significantly different between T2D and HFF controls at any timepoint, except for the t = 240 min time point when animals treated with ZT-01 (3 mg/kg) displayed significantly lower blood glucose than the T2D vehicle group (16.4 ± 0.8 vs. 19.2 ± 0.8 mmol/L, p < 0.05). Here, SSTR2 is linked to type 2 diabetes mellitus.