Borràs et al. applied LRS on pooled long-range-PCR amplicons to screen for PKD1 mutations in 19 patients with autosomal dominant polycystic kidney disease, enabling to distinguish between PKD1 and its pseudogenes and reducing the interference of homologous sequences, high GC-content or repetitive elements (Borràs et al., 2017). This evidence concerns the gene PKD1 and autosomal dominant polycystic kidney disease.