Additionally, several genes, including BLK (B lymphoid tyrosine kinase), STAT4 (signal transducer and activator of transcription 4), CXCR5 (C-X-C chemokine receptor type 5), IL12A (interleukin-12 subunit alpha), TNIP1 (TNFAIP3-interacting protein 1), and IRF5 (interferon regulatory factor 5), have been suggested as potential gene candidates for susceptibility to SjS in various studies (92). This evidence concerns the gene STAT4 and Schwartz-Jampel syndrome.