Among them, TMEM60 was the gene with the highest risk score, which belongs to the transmembrane protein family (TMEM), and TMEMs are mostly involved in adverse events related to tumors, such as TMEM88 that leads to proliferation, migration, and invasion of gastric cancer tumors through the JAK2/STAT3 pathway (82). The gene discussed is TMEM60; the disease is gastric cancer.