ESR1 and rheumatoid arthritis: • ESR (erythrocyte sedimentation rate), CRP (C-reactive protein), RF, ACPA and additional RA biomarker tests by Vectra/LabCorp or comparable supplier), Incidence: increased if elevated levels of ESR, CRP, RF, and ACPA are detected, in addition to 12 biomarkers by Vectra DA or similar multicomponent biomarker tests