MAPT and early-onset autosomal dominant Alzheimer disease: Four patients with Aβ positivity showed accumulations of 18F-florzolotau radio signals in the neocortical and limbic cortices to varying degrees, with enhancements in the inferior and lateral temporal and posterior cingulate cortices, precuneus and temporo-parietal junction, which are characteristics of Alzheimer’s disease tau pathologies (lower right images in Fig. 1A; P12–P15 in Fig. 1B).