It is noteworthy that all four cases with PNFA presented 4RT-like tau depositions according to visual reads, in concordance with the high frequency of CBD and PSP pathologies in this clinical FTD subtype.4 Moreover, 4RT deposits were indicated in two of three subjects with CBS and in one subject with FTD-PSP clinical phenotype. This evidence concerns the gene MAPT and red-green color blindness.