At least 2 of the following:1.Rash or bilateral non-purulent conjunctivitis or mucocutaneous inflammation signs (oral, hands, or feet)2.Hypotension or shock3.Features of myocardial dysfunction, pericarditis, valvulitis, or coronary abnormalities (including ECHO findings or elevated troponin/ NT-proBNP)4.Evidence of coagulopathy (by prothrombin time, activated partial thromboplastin time, elevated D-dimers)5.Acute gastrointestinal problems (diarrhea, vomiting, or abdominal pain). The gene discussed is F2; the disease is pericarditis.