To explore the status and function of CD8+ MAIT cells in COPD+ and COPD− NSCLC, we detected some important markers of CD8+ MAIT cells, including activation marker CD69, immune exhaustion marker PD1, cytotoxic markers GZMB and IFN‐γ, by flow cytometry (Figure 2A). The gene discussed is GZMB; the disease is non-small cell lung carcinoma.