To clarify the effect of HBI‐8000 on cardiac hypertrophy, we pretreated with 5 μM HBI‐8000 for 1 h, then stimulated with AngII (100 and 500 nM) for 24 h, and determined the surface area of cardiomyocytes using immunofluorescence staining (Figure S1A,B). Here, AGT is linked to cardiac hypertrophy.