TP53 and neoplasm: Neel et al. developed a platform of multiple murine Fallopian tube epithelial organoids of different genotypes (Tp53−/−; Ccne1OE; Akt2OE; KrasOE, Tp53−/−; Brca1−/−; MycOE, Tp53−/−; Pten−/−; Nf1−/−), demonstrating the significant similarity among corresponding organoids, organoid-transplanted mouse models, and patients with HGSOC in drug response, secretome, and tumor immune microenvironment (Zhang et al. 2021).