PTGDS and meningioma: There were no associations between PCDH fusions and meningioma DNA molecular group [4], CNS World Health Organization (WHO) 2021 grade [14], or gene expression risk score [2]. The second most common gene transcript fusions were translocations between prostaglandin D2 synthase (PTGDS) on chromosome 9 and actin genes on chromosomes 7 or 17 (n = 160 of 1701 gene transcript fusions events across 302 meningiomas, 9.4%) (Fig. 1a and Supplementary Table 3, online resource).