Similar to our observation in CRC tumour tissue (Supplementary Tables 20 and 21), our data show that Fna C2 is more prevalent and abundant in the stool of patients with CRC than Fna C1 (Fig. 5d and Extended Data Fig. 10) and is furthermore the only Fn subgroup significantly enriched in the stool of patients with CRC compared to healthy individuals (Extended Data Fig. 10a). The gene discussed is FN1; the disease is colorectal carcinoma.