CRHR1 and Anxiety: We then assessed CeA expression of stress-related genes, including CRF (Crh), CRF1 receptor (Crhr1), Fkbp5, brain-derived neurotrophic factor (Bdnf), and nuclear receptor subfamily 3 group C member 1 (Nr3c1; which encodes the GR), which are known to modulate anxiety and alcohol drinking [23, 33].