HSP90AA1 is upregulated in colorectal polyps with a high degreeof dysplasia and the potential for becoming malignant.97 Similarly, HSP90AB1 is commonly affected invarious malignant diseases, and reduced expression in CRC is indicativeof poor prognosis.98,99 Our proteome screening showeda reverse expression trend for HSP90AB1, as FUT8-attenuatedclones from the SW480 line overexpressed HSP90AB1, while in theirmetastatic SW620 counterparts, expression was reduced. The gene discussed is HSP90AA1; the disease is polyp of large intestine.