These eight tumor lines integratedthe experimental system to study in vitro the influence of core fucosylationon CRC malignization since the two distinctive malignant stages ofthe SW480/SW620 tandem are an accepted model of CRC progression:47,48 the nonmetastatic primary SW480 cells and metastatic SW620 cellsfrom a lymph node of the same patient.47,48 Indeed, inprevious research by our team, we verified the degree of inhibitionof FUT8 expression in the attenuated F52L/F59L clonesas well as characterizing their functional phenotype.28,29. The gene discussed is FUT8; the disease is colorectal carcinoma.