In addition, EGFR and Src have been involved in VEGF secretion leading to angiogenic tumor growth.5,49 Therefore, TAT-Cx43266–283 might reduce the aberrant vascularization found in GBMs, originated by SVZ-NSCs with GBM driver mutations, through the inhibition of the EGFR-Src axis. Here, EGFR is linked to glioblastoma.