FBN1 and infection: For instance, fibrillin 1 supports human immunodeficiency virus 1 replication independent of bone marrow stromal antigen 2 (BST-2/tetherin), an interferon-inducible transmembrane protein [54], and infection by tobacco mosaic virus leads to downregulation of chloroplastic drought-induced stress fibrillin proteins in tobacco plants (Nicotiana glutinosa L.)[53].