It is well established that the expression of the RBP HuR is upregulated in many tumor types and is considered a hub in cancer because of the function that it exerts on its target RNAs, which contribute to the main hallmarks of cancer.50 Several works had already reported increased HuR protein expression in the context of liver cancer.57,58 Accordingly, in this study we detected high ELAVL1 mRNA expression levels in a cohort of patients with HCC, independently of the tumor stage, which were associated with a lower individual survival. This evidence concerns the gene ELAVL1 and neoplasm.