To study the tumorigenic advantage of HuR SUMO modification, human hepatoma HuH-7 cells stably expressing WT HuR and the described K120R, K182R, and K120/182R SUMOylation mutant plasmids were generated by means of transfections and antibiotic selection (Figures S7A and S7B). This evidence concerns the gene ELAVL1 and hepatocellular carcinoma.