Among these core genes, THBS1 and HGF are highly expressed in AML (Fig. 6A, B), IGF1 and IL-6 are low expressed in AML (Fig. 6C, D), and CCL25, MMP7 and IL-10 are not different from healthy controls (Fig. 6E–G). The gene discussed is THBS1; the disease is acute myeloid leukemia.