CEACAM5 and colorectal cancer: In keeping with our findings, Pramanik et al. (2022) have shown that anti-CEA Affimer tagged cubosomes, loaded with copper acetylacetonate as a model drug, actively targeted LS174T colorectal cancer cells in vivo.41 The authors showed preferential accumulation in colorectal cancer mouse xenografts, while maintaining low nonspecific absorption and toxicity in other organs.