In addition, through the JAK2/STAT3 signalling pathway inhibitor Stattic also can inhibit the rise in JAK2/STAT3 signal pathway of P62,80 miR‐16‐5p can promote autophagy by upregulating Beclin 1 and downregulating P62, thus playing an inhibitory effect on bladder cancer.81 The gene discussed is SQSTM1; the disease is urinary bladder cancer.