Based on univariate and multivariate Cox regression analyses, MRPS16 mRNA overexpression was correlated to TNM stage and lymph node metastasis; hence, it was an independent prognostic factor for poor survival of LAUD patients (Table S2), indicating that MRPS16 might be a potential LAUD biomarker. The gene discussed is MRPS16; the disease is metastatic malignant neoplasm in the lymph nodes.