GLIS2 and Hyperglycemia: More accumulation of JC‐1 aggregates and less diffuse JC‐1 monomers were observed in HG + pcDNA3.1‐lncRNA Glis2 group, which indicated that the decrease of ΔΨM caused by hyperglycemia significantly reversed by lncRNA Glis2 overexpression (Figure 2H,I).