SNPs at the CSMD1 locus have been linked to several other neurological disorders, including Parkinson’s disease [208], bipolar disorder [209], multiple sclerosis [210,211], autism and learning disorders [212,213], implying that CSMD1 has a broad role in brain development and function, perhaps linked to synaptic loss, a common feature of these disorders. Here, CSMD1 is linked to bipolar disorder.