MOBP and early-onset autosomal dominant Alzheimer disease: Previous GWAS identified an association between the MOBP (myelin-associated oligodendrocyte basic protein) genetic locus at 3p22.1 (particularly the rs616147), and neurodegenerative diseases such as multiple sclerosis, Alzheimer’s disease, FTD, and progressive supranuclear palsy (Höglinger et al., 2011; Nasrabady et al., 2018).