Utilizing MQRG expression (PPARGC1A, PPARA, PPARG, NRF1, NFE2L2, TFAM, ESRRA, MFN1, MFN2, OPA1, MFF, FIS1, MIEF2, MIEF1, PINK1, PARK2, SQSTM1, MAP1LC3A, MAP1LC3B, MAP1LC3C), we categorized ACC samples into two clusters (MQRG low, Cluster A, and high, Cluster B) and examined the significant differences in gene expression between these groups. This evidence concerns the gene OPA1 and adrenal cortex carcinoma.