Utilizing MQRG expression (PPARGC1A, PPARA, PPARG, NRF1, NFE2L2, TFAM, ESRRA, MFN1, MFN2, OPA1, MFF, FIS1, MIEF2, MIEF1, PINK1, PARK2, SQSTM1, MAP1LC3A, MAP1LC3B, MAP1LC3C), we categorized ACC samples into two clusters (MQRG low, Cluster A, and high, Cluster B) and examined the significant differences in gene expression between these groups. The gene discussed is MIEF1; the disease is adrenal cortex carcinoma.