INS and cardiomyopathy: Moreover, the cardiomyopathy in Atp6v0d1AKO mice can be rescued by increasing systemic insulin sensitivity with Rosiglitazone (Figure S6), similar to that observed in Bscl2-/- mice 42, demonstrating the prominent feature of lipodystrophy cardiomyopathy that had been observed in the well-established Bscl2-/- lipodystrophy mice.