Spatial modulation of EMILIN1 expression coincides with CD8+ T-cell infiltration and is predictive of patient survival. To support the hypothesis that EMILIN1 expression is locally inhibiting TGF-β signaling, we monitored EMILIN1 and TGFBI spatial expression by immunofluorescence analysis in 5 patients with BC. This evidence concerns the gene CD8A and breast cancer.