FLT1 and lip and oral cavity carcinoma: Similar results were obtained in the study reported by (Hwang-Bo et al., 2018), in which 3-acetyloleanolic acid isolated from the seeds of Vigna sinensis K. exhibited inhibition of VEGF-A-induced lymph-angiogenesis both in vitro and in vivo through suppressing VEGF-A-VEGFR-1 and -2 signaling in human lymphatic microvascular endothelial cells (HLMECs) and oral cancer sentinel lymph node animal model (OCSLN).