SQSTM1 and diabetes mellitus: Interestingly, as Liu et al. (2019a) found that notoginsenoside Fc counld accelerate re-endothelialization after vascular injury in diabetic rats by promoting endothelial cell autophagy (including LC3B, Beclin-1, P62/SQTM1 targets), indicating that notoginsenoside Fc might have therapeutic benefits for early endothelial damage and restenosis after intervention for diabetes-related vascular diseases.