RUNX3 and gastric cancer: Luo et al. (2020) reported that sponging circ_CCDC9 inhibits miR-6792-3p expression by antagonizing the proliferation, migration, and invasion of GC. Yu with colleagues found that circ_0021087 sponges miR-184, decreasing tumorigenesis in GC cells (Yu et al., 2021). Similarly, another study confirmed that circ_REPS2 can sponge miR-558 to inhibit GC progression by regulating RUNX3 (Guo et al., 2020).