The plasma of patients with decompensated cirrhosis was shown to induce NET formation in isolated neutrophils from healthy controls (Sehgal et al., 2022), and levels of H3Cit-DNA, myeloperoxidase (MPO)-DNA, and cell-free DNA (markers of NET formation) were shown to be significantly elevated in patients with cirrhosis compared to healthy controls, which was associated with cirrhosis severity (Blasi et al., 2019; Zenlander et al., 2021). Here, MPO is linked to Cirrhosis.